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Mood Stabilizers

Chemical Class Generic Name Trade Name

Known Side Effects

Lithium Salt Lithium carbonate
Lithium citrate
Lithotabs
Eskalith
Duralith
Cibalith-S
  • Drowsiness, slurred speech
  • Bradycardia (slow heart rate)
  • Nausea, vomiting
  • Excessive thirst
  • Weight gain
  • Dry skin, rash and folliculitis (inflammation of hair follicles), common
  • Hypothyroidism occurs with long-term use (underactive thyroid gland)
Anticonvulsants Clonazepam
Phenytoin
Carbamazepine
Davalproex sodium
Gabapentin
Oxcarbazepine
Klonopin
Dilantin
Tegretol
Depakote
Neurontin
Trileptal
  • Nausea, vomiting
  • Behavior changes/deterioration
  • Fine motor tremor (especially in lips, fingers)
  • Changes in appetite, severe weight gain
Tryptophan l-Tryptophan Triptan
  • Drowsiness
  • Headache
  • Tremors
  • Euphoria

Antidepressants

Chemical Class Generic Name Trade Name Known Side Effects
Selective Serotonin Reuptake Inhibitors (SSRI) Citalopram
Escitalopram
Fluvoxamine
Paroxetine
Fluoxetine
Sertaline
Celexa
Lexapro
Luvox
Paxil
Prozac
Zoloft
  • Headache, drowsiness
  • Fine motor tremor, dysphasia (speech impairment)
  • Nausea, diarrhea, weight gain
  • Rhinitis (nasal inflammation)
  • Risk of seizure
Norepinephrine Dopamine Reuptake Inhibitor (NDRI) Bupropion Wellbutrin
  • Nervousness
  • Vivid dreams/nightmares
  • Nausea, heartburn, loss of appetite
  • Elevated blood pressure
  • Skin rash
  • Yellow tinge around the eyes
  • Chest pain, seizure risk
Selective Serotonin Norepinephrine Reuptake Inhibitor (SNRI) Venlafaxine
Duloxetine
Effexor
Cymbalta
  • Nervousness
  • Dry mouth
  • Constipation
  • Elevated blood pressure
  • Persistent headache
  • Severe muscle twitching/tremor
Non-selective Cyclic Antidepressants Amitriptyline
Clomipramine
Doxepin
Amoxapine
Maprotiline
Elavil
Anafranil
Sinequan
Asendin
Ludiomil
  • Drowsiness/fatigue
  • Blurred vision
  • Dry mouth
  • Dizziness
  • Muscle tremor
  • Swelling of the face
  • Soreness of the mouth/gums/throat
  • Inability to pass urine/have a bowel movement
Reversible Inhibitor of MAO-A (RIMA) Moclobemide Manerix
  • Blurred vision
  • Hypotension (abnormally low blood pressure)
  • Nausea/constipation
  • Dangerous interactions with virtually every over-the-counter medication
  • Highly specialized diet required for duration of treatment
Irreversible Monoamine Oxidase Inhibitors Isocarboxazid
Phenelzine
Tranylcypromine
Marplan
Nardil
Parnate
  • Drowsiness
  • Increase symptoms of mania in patients diagnosed with bipolar disorder
  • Edema in lower extremities (abnormal swelling)
  • Increased appetite/weight gain
  • Dangerous interactions with virtually every over-the-counter medication
  • Highly specialized diet required for duration of treatment

Antipsychotics

Chemical Class Generic Name Trade Name Known Side Effects
"Conventional" (Typical) Antipsychotics Haloperidol
Loxapine
Molindone
Pimozide
Chlorpromazine
Fluphenazine
Thiothixene
Haldol
Loxapine
Moban
Orap
Thorazine
Prolixin
Navane
  • Potential for liver damage with long-term use
  • Dysphagia (difficulty swallowing)
  • Incontinence
  • Blurred vision, dry eyes
  • Tachycardia (rapid heart rate)
  • Severe weight gain
"Second Generation" (Atypical Antipsychotics) Risperidone
Clozapine
Quetiapine
Olanzapine
Ziprasidone
Risperdal
Clozaril
Seroquel
Zyprexa
Geodon
  • Sedation, fatigue, insomnia
  • Lower lip tremor, loss of gag reflex
  • Dry mucus membranes, constipation
  • Severe weight gain
  • Bradycardia (slow heart rate)
  • Hyperglycemia (abnormally high blood glucose), anorexia, edema (abnormal swelling) with prolonged usage
"Third Generation" Antipsychotic Aripiprazole Abilify
  • Headache
  • Insomnia
  • Dizziness
  • Nausea, constipation

ADHD Drugs

Chemical Class Generic Name Trade Name Known Side Effects
Psychostimulant Dexotroamphetamine
Amphetamine salts
Methylphenidate
Dexmethylphenidate
Magnesium pemoline
Dexedrine
Adderall
Ritalin
Focalin
Cylert
  • May interfere with liver function
  • Tics
  • Amplifies symptoms of other psychiatric disorders
  • GI distress, weight loss, anorexia
  • Lowers seizure threshold
Selective norepinephrine reuptake inhibitor Atomoxetine Strattera
  • Rhinitis (nasal inflammation)
  • Upper abdominal pain
  • Sexual dysfunction
  • Can cause SEVERE liver injury

Adrenergic agent

Clonidine Catapres
  • Hypotension (abnormally low blood pressure)
  • Anxiety
  • Dermatological indications common (dry skin, rash)
  • May increase agitation

Anti-Anxiety Drugs (Anxiolytics)

Chemical Class Generic Name Trade Name Known Side Effects

Selective Serotonin Reuptake Inhibitors (SSRIs)

Citalopram
Escitalopram
Fluvoxamine
Paroxetine
Fluoxetine
Sertaline
Celexa
Lexapro
Luvox
Paxil
Prozac
Zoloft
  • Headache, drowsiness
  • Fine motor tremor, dysphasia (speech impairment)
  • Nausea, diarrhea, weight gain
  • Rhinitis (nasal inflammation)
  • Risk of seizure

Antihistamine

Hydroxyzine
Diphenhydramine
Doxylamine
Atarax
Benadryl
Unisom
  • Daytime sedation
  • Anterograde amnesia (loss of memory directly after taking drug)
  • Rebound insomnia
  • Can impair blood pressure and respiration

Azaspirone

Buspirone Buspar
  • Headache, dizziness
  • Possible dopamine receptor inhibition (inhibits release of dopamine-a brain chemical vital to the central nervous system)
  • Can precipitate bipolar episode

Barbiturates

Phenobarbital
Secobarbital
Nembutal
Seconal
  • High risk of physical dependency
  • Extreme sedation
  • Can impair blood pressure and respiration

Benzodiazepines

Alprazolam
Lorazepam
Chlordiazepoxide
Triazolam
Diazepam
Xanax
Ativan
Librium
Halcion
Valium
  • Impaired cognitive processing abilities
  • Confusion, disorientation
  • Excessive doses can cause respiratory distress
  • Muscle weakness, ataxia (loss of voluntary muscle movement)
  • Dizziness, increased salivation